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CMA1 抗体

(Chymase 1, Mast Cell (CMA1))
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008].

64 results :

Verified CMA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN768626
 
CMA1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7073506
 
CMA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263136
 
CMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7445774
 
CMA1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7436312
 
CMA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147732
 
CMA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147734
 
CMA1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7436315
 
CMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53046 unconjugated
产品编号 ABIN6242796
 
CMA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN2619354
 
CMA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138762
 
CMA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN929416
 
CMA1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1G11 unconjugated
产品编号 ABIN6942587
 
CMA1 适用: 小鼠 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7177106
 
CMA1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7147737
 
CMA1 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7147735
 
CMA1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7147736
 
CMA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7636945
 
CMA1 适用: 小鼠 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7177108
 
CMA1 适用: 小鼠 宿主: 兔 Polyclonal FITC
产品编号 ABIN7177107
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Immunofluorescence (IF)
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 适用
    • Human
    • Mouse
    • Rat
    • Cow
    • Dog
    • Guinea Pig
    • Rabbit
    • Sheep
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 18C83
    • 1G11
    • 2Q1506
    • B7
    • CC1
    • RB53046
  • 抗原表位
    • AA 22-247
    • AA 22-246
    • AA 9-247
    • AA 22-146
    • C-Term
    • AA 20-247
    • AA 22-197
    • AA 1-247
    • AA 81-247
    • AA 84-118
    • Internal Region
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • 抗体亚型
    • IgG
    • IgG1
    • IgG1 kappa
    • Ig Fraction
    • IgG2a
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Abbexa
    • Signalway
    • Biomatik
    • Cloud-Clone
    • Acris
    • Aviva Systems Biology
    • Boster Bio
    • CUSABIO
    • USBio

Latest Publications for our CMA1 抗体

Germundson, Smith, Vendsel, Kelsch, Combs, Nagamoto-Combs: "Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 120, (2019) (PubMed).

Moretti, Renga, Oikonomou, Galosi, Pariano, Iannitti, Borghi, Puccetti, De Zuani, Pucillo, Paolicelli, Zelante, Renauld, Bereshchenko, Sportoletti, Lucidi, Russo, Colombo, Fiscarelli, Lass-Flörl et al.: "A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis. ..." in: Nature communications, Vol. 8, pp. 14017, (2017) (PubMed).

McLeod, Bhutto, Edwards, Gedam, Baldeosingh, Lutty: "Mast Cell-Derived Tryptase in Geographic Atrophy." in: Investigative ophthalmology & visual science, Vol. 58, Issue 13, pp. 5887-5896, (2017) (PubMed).

Sansoè, Aragno, Mastrocola, Mengozzi, Novo, Parola: "Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162644, (2016) (PubMed).

Zhao, Wang, Lin, Groban: "GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number." in: Biochemical and biophysical research communications, Vol. 459, Issue 1, pp. 131-6, (2015) (PubMed).

Zheng, Wei, Hase, Shi, Killingsworth, Litovsky, Powell, Kobayashi, Ferrario, Rab, Aban, Collawn, DellItalia: "Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog." in: PLoS ONE, Vol. 9, Issue 4, pp. e94732, (2014) (PubMed).

Wang, Jessup, Zhao, Da Silva, Lin, MacNamara, Ahmad, Chappell, Ferrario, Groban: "Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats." in: PLoS ONE, Vol. 8, Issue 10, pp. e76992, (2013) (PubMed).

Heikkilä, Lätti, Leskinen, Hakala, Kovanen, Lindstedt: "Activated mast cells induce endothelial cell apoptosis by a combined action of chymase and tumor necrosis factor-alpha." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 2, pp. 309-14, (2008) (PubMed).

Hsieh, Sharma, Gibbons, Goggans, Erzurum, Haque: "Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 40, pp. 14380-5, (2005) (PubMed).

Aliases for CMA1 抗体

chymase 1 (CMA1) 抗体
chymase 1 (Cma1) 抗体
chymase 1, mast cell (CMA1) 抗体
chymase 1, mast cell (Cma1) 抗体
chymase-like (LOC100008644) 抗体
chymase 抗体
Chymase 抗体
CMA1 抗体
CYH 抗体
Mcp-5 抗体
MCP3P 抗体
Mcp5 抗体
Mcpt5 抗体
MCT1 抗体
MMCP-5 抗体
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