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Claudin 16 蛋白

(Claudin 16 (CLDN16))
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. [provided by RefSeq, Jun 2010].

5 results :

custom-made CLDN16 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7560286
 
CLDN16 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1349596
 
CLDN16 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, SDS, Imm, PC
产品编号 ABIN7407367
 
custom-made CLDN16 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3127822
 
CLDN16 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS
产品编号 ABIN6378535
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
    • Positive Control (PC)
  • 适用
    • Mouse
    • Rat
    • Human
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-235
    • AA 1-305
  • 标记
    • His tag
    • GST tag
    • Strep Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • Abbexa

Aliases for Claudin 16 蛋白

claudin 16 (CLDN16) 蛋白
claudin 16 (Cldn16) 蛋白
claudin-16 蛋白
CLDN16 蛋白
HOMG3 蛋白
PCLN1 蛋白
Pcln1 蛋白
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