CITED4 蛋白
(Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 4 (CITED4))
The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. [provided by RefSeq, Aug 2011].
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CITED4
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Aliases for CITED4 蛋白
similar to Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal (CITED4) 蛋白Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 (CITED4) 蛋白
Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 4 (cited4) 蛋白
Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 4 L homeolog (cited4.L) 蛋白
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 (Cited4) 蛋白
cCITED3 蛋白
CITED3 蛋白
CITED4 蛋白
MRG-2 蛋白
Mrg2 蛋白
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