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CIB1 产品

(Calcium and Integrin-Binding Protein 1 (CIB1))

Categories

This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Featured CIB1 Categories

CIB1 抗体

High quality antibodies with extensive validation data.

CIB1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CIB1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CIB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (3)
Cat. No. ABIN564584
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (2)
Cat. No. ABIN969057
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881205
Quantity 400 μL
Datasheet Datasheet

Recommended CIB1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN584159
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN584160
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1124728
Quantity 96 tests
Datasheet Datasheet

Recommended CIB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666637
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349464
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418515
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CIB1 Products

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Jarman, Moretti, Zebol, Pitson: "Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1." in: The Journal of biological chemistry, Vol. 285, Issue 1, pp. 483-92, (2009) (PubMed).

Yamniuk, Anderson, Fraser, Vogel: "Auxiliary Ca2+ binding sites can influence the structure of CIB1." in: Protein science : a publication of the Protein Society, Vol. 18, Issue 5, pp. 1128-34, (2009) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Denofrio, Yuan, Temple, Gentry, Parise: "Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members." in: Thrombosis and haemostasis, Vol. 100, Issue 5, pp. 847-56, (2008) (PubMed).

White, Yang, Monteiro, Foskett: "CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20825-33, (2006) (PubMed).

Yuan, Leisner, McFadden, Wang, Larson, Clark, Boudignon-Proudhon, Lam, Parise: "CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation." in: The Journal of cell biology, Vol. 172, Issue 2, pp. 169-75, (2006) (PubMed).

Yuan, Leisner, McFadden, Clark, Hiller, Maeda, OBrien, Parise: "CIB1 is essential for mouse spermatogenesis." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8507-14, (2006) (PubMed).

Gentry, Singer, Betts, Yang, Ferrara, Sondek, Parise: "Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8407-15, (2005) (PubMed).

Synonyms and alternative names related to CIB1

calcium and integrin binding 1 (calmyrin) (cib1), calcium and integrin-binding protein 1 (CpipJ_CPIJ003501), calcium and integrin binding 1 (CIB1), calcium and integrin binding 1 (cib1), Calcium and integrin-binding protein 1 (kip1), calcium and integrin binding 1 (calmyrin) (Cib1), calcium and integrin binding 1 (Cib1), CIB, Cib, Cibkip, CIBP, Kip, KIP1, PRKDCIP, Prkdcip, SIP2-28, Sip2-28, zgc:112015

Protein level used designations for CIB1

  • calcium and integrin-binding protein 1
  • calcium and integrin binding protein 1
  • Calcium and integrin-binding protein 1
  • DNA-PK interaction protein
  • DNA-PKcs-interacting protein
  • DNA-dependent protein kinase interacting protein
  • SNK-interacting protein 2-28
  • CIB
  • calcium and integrin binding, protein kinase interacting protein
  • calmyrin
  • kinase-interacting protein
  • protein kinase, DNA activated, catalytic polypeptide interacting protein
  • KIP
  • calcium- and integrin-binding protein
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