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ChT 产品

(High Affinity Choline Transporter (ChT))
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM, Mar 2008].

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Featured ChT Categories

ChT 抗体

High quality antibodies with extensive validation data.

ChT ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ChT 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ChT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (fro), IHC (p)
Validations
  • (1)
  • (1)
Cat. No. ABIN534020
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7267643
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IP, ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN1742430
Quantity 100 μg
Datasheet Datasheet

Recommended ChT ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6956523
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674900
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674901
Quantity 96 tests
Datasheet Datasheet

Recommended ChT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3117983
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3124742
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406950
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ChT Products

Penet, Shah, Bharti, Krishnamachary, Artemov, Mironchik, Wildes, Maitra, Bhujwalla: "Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 2, pp. 386-95, (2015) (PubMed).

Misawa, Fujigaya, Nishimura, Moriwaki, Okuda, Kawashima, Nakata, Ruggiero, Blakely, Nakatsu, Ohno: "Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice." in: The European journal of neuroscience, Vol. 27, Issue 12, pp. 3109-17, (2008) (PubMed).

Ferguson, Savchenko, Apparsundaram, Zwick, Wright, Heilman, Yi, Levey, Blakely: "Vesicular localization and activity-dependent trafficking of presynaptic choline transporters." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 30, pp. 9697-709, (2003) (PubMed).

Kus, Borys, Ping Chu, Ferguson, Blakely, Emborg, Kordower, Levey, Mufson: "Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system." in: The Journal of comparative neurology, Vol. 463, Issue 3, pp. 341-57, (2003) (PubMed).

Apparsundaram, Ferguson, George, Blakely: "Molecular cloning of a human, hemicholinium-3-sensitive choline transporter." in: Biochemical and biophysical research communications, Vol. 276, Issue 3, pp. 862-7, (2000) (PubMed).

Synonyms and alternative names related to ChT

solute carrier family 5 member 7 (SLC5A7), solute carrier family 5 (choline transporter), member 7 (Slc5a7), solute carrier family 5 member 7 (Slc5a7), CHT, CHT1, Cht1, hCHT, HMN7A

Protein level used designations for ChT

  • hemicholinium-3-sensitive choline transporter
  • high affinity choline transporter 1
  • high affinity choline transporter; hemicholinium-3-sensitive choline transporter
  • solute carrier family 5 (choline transporter), member 7
  • solute carrier family 5 member 7
  • CHT
  • solute carrier family 5, member 7
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