CDK14 抗体
(Cyclin-Dependent Kinase 14 (CDK14))
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
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Latest Publications for our CDK14 抗体
: "Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation." in: The Journal of biological chemistry, Vol. 291, Issue 51, pp. 26427-26434, (2017) (PubMed).: "Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma." in: British journal of cancer, Vol. 106, Issue 5, pp. 947-54, (2012) (PubMed).
: "Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 45, pp. 14309-22, (2009) (PubMed).
: "Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1." in: FEBS letters, Vol. 583, Issue 13, pp. 2171-8, (2009) (PubMed).
: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).
: "Identification and cellular localization of human PFTAIRE1." in: Gene, Vol. 267, Issue 2, pp. 165-72, (2001) (PubMed).
Aliases for CDK14 抗体
cyclin dependent kinase 14 (CDK14) 抗体cyclin-dependent kinase 14 (Cdk14) 抗体
cyclin-dependent kinase 14 L homeolog (cdk14.L) 抗体
mKIAA0834 抗体
PFTAIRE1 抗体
pftaire1 抗体
PFTK1 抗体
Pftk1 抗体
pftk1 抗体
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