CD68 抗体
(CD68 Molecule (CD68))
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].
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Latest Publications for our CD68 抗体
: "Biochemical analyses of cystatin-C dimers and cathepsin-B reveals a trypsin-driven feedback mechanism in acute pancreatitis." in: Nature communications, Vol. 16, Issue 1, pp. 1702, (2025) (PubMed).: "A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better." in: Molecular cancer, Vol. 22, Issue 1, pp. 182, (2023) (PubMed).
: "Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release." in: Nature communications, Vol. 14, Issue 1, pp. 6322, (2023) (PubMed).
: "IRAK3-mediated suppression of pro-inflammatory MyD88/IRAK signaling affects disease severity in acute pancreatitis." in: Scientific reports, Vol. 13, Issue 1, pp. 10833, (2023) (PubMed).
: "Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis." in: Gut, Vol. 72, Issue 7, pp. 1355-1369, (2023) (PubMed).
: "Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice." in: Journal of biomechanics, Vol. 141, pp. 111179, (2022) (PubMed).
: "Industrial Processing Induces Pericardial Patch Degeneration." in: Frontiers in surgery, Vol. 9, pp. 881433, (2022) (PubMed).
: "Mobilization of CD11b+/Ly6chi monocytes causes multi organ dysfunction syndrome in acute pancreatitis." in: Frontiers in immunology, Vol. 13, pp. 991295, (2022) (PubMed).
: "Elevated IL-15 concentrations in the sarcoidosis lung is independent of granuloma burden and disease phenotypes." in: American journal of physiology. Lung cellular and molecular physiology, (2021) (PubMed).
: "Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution." in: Cell death & disease, Vol. 12, Issue 6, pp. 589, (2021) (PubMed).
Aliases for CD68 抗体
CD68 molecule (CD68) 抗体CD68 antigen (Cd68) 抗体
Cd68 molecule (Cd68) 抗体
gp110 抗体
GP110 抗体
Lamp4 抗体
LAMP4 抗体
Scard1 抗体
SCARD1 抗体
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