CD40 抗体
(CD40)
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Latest Publications for our CD40 抗体
: "Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." in: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).: "Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 12, pp. 4838-4847, (2017) (PubMed).
: "Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse Model." in: Endocrinology, Vol. 157, Issue 10, pp. 3771-3778, (2016) (PubMed).
: "Decreased expression of follicular dendritic cell-secreted protein correlates with increased immunoglobulin A production in the tonsils of individuals with immunoglobulin A nephropathy." in: Translational research : the journal of laboratory and clinical medicine, Vol. 166, Issue 3, pp. 281-91, (2015) (PubMed).
: "Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 1, pp. 22-35, (2014) (PubMed).
: "A Short History of the B-Cell-Associated Surface Molecule CD40." in: Frontiers in immunology, Vol. 5, pp. 472, (2014) (PubMed).
: "Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-Guérin." in: European journal of immunology, Vol. 44, Issue 1, pp. 80-92, (2014) (PubMed).
: "The cell-to-cell coordination between activated T cells and CpG-stimulated macrophages synergistically induce elevated levels of IL-10 via NF-κB1, STAT3, and CD40/CD154." in: Cell communication and signaling : CCS, Vol. 11, pp. 95, (2014) (PubMed).
: "High-content cytometry and transcriptomic biomarker profiling of human B-cell activation." in: The Journal of allergy and clinical immunology, Vol. 133, Issue 1, pp. 172-80.e1-10, (2014) (PubMed).
: "CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction." in: Basic research in cardiology, Vol. 108, Issue 6, pp. 386, (2013) (PubMed).
Aliases for CD40 抗体
CD40 molecule (CD40) 抗体CD40 antigen (Cd40) 抗体
CD40 molecule (Cd40) 抗体
AI326936 抗体
Bp50 抗体
CDW40 抗体
GP39 抗体
HIGM1 抗体
IGM 抗体
IMD3 抗体
p50 抗体
T-BAM 抗体
TNFRSF5 抗体
Tnfrsf5 抗体
TNFSF5 抗体
TRAP 抗体
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