CD33 蛋白
(CD33)
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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41 results
CD33
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
CD33
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, ELISA, WB, AcA, Imm
Active
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 85 % as determined by reducing SDS-PAGE.
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
CD33
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
>95 %
SDS, ELISA, WB, IP
1 image
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
1 image
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
MALS verified
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
95 %
CD33
宿主: 人
宿主: 人细胞
Recombinant
Greater than 95 % as determined by SEC-HPLC and reducing SDS-PAGE.
SDS, ELISA, WB, MS
MALS verified
CD33
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Latest Publications for our CD33 蛋白
: "Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression." in: Scientific reports, Vol. 7, Issue 1, pp. 270, (2017) (PubMed).: "Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia." in: Oncoimmunology, Vol. 5, Issue 9, pp. e1211220, (2016) (PubMed).
Aliases for CD33 蛋白
CD33 molecule (CD33) 蛋白CD33 antigen (Cd33) 蛋白
CD33 molecule (Cd33) 蛋白
gp67 蛋白
p67 蛋白
SIGLEC-3 蛋白
Siglec-3 蛋白
SIGLEC3 蛋白
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