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C-Type Lectin Domain Family 4, Member M 蛋白

(C-Type Lectin Domain Family 4, Member M (CLEC4M))

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].

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C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (His tag) (ABIN7553516)

custom-made CLEC4M 宿主: 人宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

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CLEC4M 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

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CLEC4M 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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C-Type Lectin Domain Family 4, Member M 蛋白 by Grade

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C-Type Lectin Domain Family 4, Member M 蛋白 by Origin

Find C-Type Lectin Domain Family 4, Member M 蛋白 for a variety of species such as anti-Human C-Type Lectin Domain Family 4, Member M, anti-Chimpanzee C-Type Lectin Domain Family 4, Member M. The species listed below are among those available. Click on a link to go to the corresponding products.

C-Type Lectin Domain Family 4, Member M 蛋白 by Source

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C-Type Lectin Domain Family 4, Member M 蛋白 by 蛋白类型

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Popular C-Type Lectin Domain Family 4, Member M 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7553516

Quantity 1 mg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7504305

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) 蛋白

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7504304

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7575759

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 73-376) (Active) protein (Fc Tag)

Reactivity Human

Source Mammalian Cells

Validations

Cat. No. ABIN7607714

Quantity 50 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) protein (Fc Tag)

Reactivity Human

Source Mammalian Cells

Validations

Cat. No. ABIN7575758

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 242-399) protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7413766

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) protein (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7194490

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 72-399) protein (hIgG-His-tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7596335

Quantity 500 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (Strep Tag)

Reactivity Human

Source Cell-free protein synthesis (CFPS)

Validations

Cat. No. ABIN3118083

Quantity 250 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713616

Quantity 20 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2716811

Quantity 20 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-445) protein (His tag)

Reactivity Chimpanzee

Source Yeast

Validations

Cat. No. ABIN1636713

Quantity 1 mg

Datasheet Datasheet

Aliases for C-Type Lectin Domain Family 4, Member M 蛋白

C-type lectin domain family 4 member M (CLEC4M) 蛋白
CD209B 蛋白
CD209L 蛋白
CD299 蛋白
DC-SIGN2 蛋白
DC-SIGNR 蛋白
DCSIGNR 蛋白
HP10347 蛋白
L-SIGN 蛋白
LSIGN 蛋白

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C-Type Lectin Domain Family 4, Member M 蛋白 by Grade

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C-Type Lectin Domain Family 4, Member M 蛋白 by 应用范围

C-Type Lectin Domain Family 4, Member M 蛋白 by 生物活性

Popular C-Type Lectin Domain Family 4, Member M 蛋白

Aliases for C-Type Lectin Domain Family 4, Member M 蛋白

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