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C-Type Lectin Domain Family 4, Member M 蛋白

(C-Type Lectin Domain Family 4, Member M (CLEC4M))
This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].

13 results :

custom-made CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7553516
 
CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
产品编号 ABIN7504305
 
CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504304
 
CLEC4M 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA
产品编号 ABIN7575759
 
CLEC4M 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
产品编号 ABIN7607714
 
CLEC4M 宿主: 人 宿主: Mammalian Cells Recombinant SDS, WB, ELISA
产品编号 ABIN7575758
 
CLEC4M 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % SDS, WB, Imm, PC
产品编号 ABIN7413766
 
CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7194490
 
CLEC4M 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95% by SDS - PAGE SDS
产品编号 ABIN7596335
 
custom-made CLEC4M 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3118083
 
CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713616
 
CLEC4M 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2716811
 
CLEC4M 宿主: Chimpanzee 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1636713
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Standard (STD)
    • Activity Assay (AcA)
    • Positive Control (PC)
  • 适用
    • Human
    • Chimpanzee
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Cell-free protein synthesis (CFPS)
    • Yeast
  • 抗原表位
    • AA 1-399
    • AA 71-399
    • AA 242-399
    • AA 71-445
    • AA 72-399
    • AA 73-376
    • Transcript Variant 1
    • Transcript Variant 2
  • 标记
    • His tag
    • Fc Tag
    • Myc-DYKDDDDK Tag
    • His-DYKDDDDK Tag
    • Strep Tag
    • hIgG-His-tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene
    • CUSABIO

Aliases for C-Type Lectin Domain Family 4, Member M 蛋白

C-type lectin domain family 4 member M (CLEC4M) 蛋白
CD209B 蛋白
CD209L 蛋白
CD299 蛋白
DC-SIGN2 蛋白
DC-SIGNR 蛋白
DCSIGNR 蛋白
HP10347 蛋白
L-SIGN 蛋白
LSIGN 蛋白
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