Caspase 6 蛋白
(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].
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8 results
CASP6
宿主: Cow
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
CASP6
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
CASP6
宿主: Cow
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
Latest Publications for our Caspase 6 蛋白
: "Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis." in: Human & experimental toxicology, Vol. 33, Issue 7, pp. 761-71, (2015) (PubMed).: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).
: "Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-1 receptor-associated kinase-M." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 1, pp. 403-10, (2010) (PubMed).
: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).
: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).
: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).
: "Role of the executioner caspases during lens development." in: The Journal of biological chemistry, Vol. 280, Issue 34, pp. 30263-72, (2005) (PubMed).
: "Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41850-6, (2002) (PubMed).
Aliases for Caspase 6 蛋白
caspase 6 L homeolog (casp6.L) 蛋白caspase 6 (casp6) 蛋白
caspase 6, apoptosis-related cysteine peptidase (casp6) 蛋白
group XIIA secretory phospholipase A2 (CASP6) 蛋白
caspase-6 (CpipJ_CPIJ017008) 蛋白
caspase 6 (Casp6) 蛋白
caspase 6 (CASP6) 蛋白
CASP6 蛋白
casp6 蛋白
caspase-6 蛋白
mCASP-6 蛋白
mch2 蛋白
Mch2 蛋白
MCH2 蛋白
xCaspase-6 蛋白
zgc:112960 蛋白
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