BAZ2A 产品
(Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A))
Categories
Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys- 16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter\; pRNA- binding is required for heterochromatin formation and rDNA silencing (By similarity).
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BAZ2A 抗体
High quality antibodies with extensive validation data.
Recommended BAZ2A 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC
Validations
- (5)
Cat. No.
ABIN7265937
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF, ICC
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- (2)
Cat. No.
ABIN6258712
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ChIP
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Cat. No.
ABIN5775093
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Recommended BAZ2A 蛋白
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Reactivity
Source
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Cat. No.
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Datasheet
Reactivity
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Source
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Validations
- (1)
Cat. No.
ABIN1346454
Quantity
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Datasheet
Datasheet
Synonyms and alternative names related to BAZ2A
bromodomain adjacent to zinc finger domain, 2A (Baz2a), bromodomain adjacent to zinc finger domain, 2A (baz2a), bromodomain adjacent to zinc finger domain 2A (BAZ2A), bromodomain adjacent to zinc finger domain 2A (baz2a), bromodomain adjacent to zinc finger domain 2A L homeolog (baz2a.L), AA415431, bax2a, C030005G16Rik, C78388, mKIAA0314, tip5, TIP5, Tip5, walp3, WALp3, Walp3, zgc:101601Protein level used designations for BAZ2A
- bromodomain adjacent to zinc finger domain protein 2A
- bromodomain adjacent to zinc finger domain, 2A
- bromodomain adjacent to zinc finger domain protein 2A-like
- TTF-I interacting peptide 5
- TTF-I-interacting protein 5
- hWALp3
- transcription termination factor I-interacting protein 5
- Transcription termination factor I-interacting protein 5
- putative chromatin remodelling factor BAZ2A
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