-
- 抗原 See all BAZ2A 抗体
- BAZ2A (Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A))
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This BAZ2A antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 原理
- BAZ2A Rabbit pAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of Human BAZ2A.
- 亚型
- IgG
-
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (N-Term) antibody
BAZ2A 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) antibodyBAZ2A 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (AA 97-266) antibodyBAZ2A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (N-Term) antibodyBAZ2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (AA 1-1905) antibodyBAZ2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- BAZ2A (Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A))
- 别名
- BAZ2A (BAZ2A 产品)
- 别名
- zgc:101601 antibody, tip5 antibody, bax2a antibody, walp3 antibody, TIP5 antibody, WALp3 antibody, AA415431 antibody, C030005G16Rik antibody, C78388 antibody, Tip5 antibody, Walp3 antibody, mKIAA0314 antibody, bromodomain adjacent to zinc finger domain, 2A antibody, bromodomain adjacent to zinc finger domain 2A antibody, bromodomain adjacent to zinc finger domain 2A L homeolog antibody, Baz2a antibody, baz2a antibody, BAZ2A antibody, baz2a.L antibody
- 背景
- Regulatory subunit of the ATP-dependent NoRC-1 and NoRC-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. Directly stimulates the ATPase activity of SMARCA5 in the NoRC-5 ISWI chromatin remodeling complex. The NoRC-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NoRC-5 ISWI chromatin remodeling complex. Within the NoRC-5 ISWI chromatin remodeling complex, mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing (By similarity. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription (By similarity. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac, leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac (By similarity. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter, pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity.,TIP5,WALp3,BAZ2A / TIP5,BAZ2A,Epigenetics & Nuclear Signaling,BAZ2A
- 基因ID
- 11176
- UniProt
- Q9UIF9
-
You are here:
