BCAM 产品
(Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
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This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Featured BCAM Categories
BCAM 抗体
High quality antibodies with extensive validation data.
BCAM ELISA试剂盒
Reliable ELISA kits for a wide range of species.
BCAM 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BCAM 抗体
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Reactivity
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Reactivity
Human
Application
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- (6)
Cat. No.
ABIN7442009
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
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Cat. No.
ABIN7193338
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0.1 mg
Datasheet
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Reactivity
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- (3)
Cat. No.
ABIN7145263
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100 μg
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Recommended BCAM ELISA试剂盒
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Reactivity
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Analytical Method
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Cat. No.
ABIN6954046
Quantity
96 tests
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Reactivity
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Quantitative Sandwich ELISA
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Cat. No.
ABIN5510708
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96 tests
Datasheet
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Reactivity
Mouse
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Cat. No.
ABIN5510709
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Datasheet
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Recommended BCAM 蛋白
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Reactivity
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Source
HEK-293 Cells
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Cat. No.
ABIN7273932
Quantity
100 μg
Datasheet
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Reactivity
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Cat. No.
ABIN7273935
Quantity
100 μg
Datasheet
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Reactivity
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Latest Publications for our BCAM Products
: "An Anti-Human Lutheran Glycoprotein Phage Antibody Inhibits Cell Migration on Laminin-511: Epitope Mapping of the Antibody." in: PLoS ONE, Vol. 12, Issue 1, pp. e0167860, (2017) (PubMed).: "BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 19, pp. 4923-4933, (2016) (PubMed).
: "Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11512-21, (2014) (PubMed).
: "The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein." in: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 30990-1001, (2013) (PubMed).
: "An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5." in: PLoS ONE, Vol. 6, Issue 8, pp. e23329, (2011) (PubMed).
: "Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of ..." in: Journal of bacteriology, Vol. 189, Issue 11, pp. 3977-86, (2007) (PubMed).
: "A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane." in: Blood, Vol. 101, Issue 10, pp. 4180-8, (2003) (PubMed).
Synonyms and alternative names related to BCAM
basal cell adhesion molecule (Lutheran blood group) (bcam), basal cell adhesion molecule (Lutheran blood group) L homeolog (bcam.L), basal cell adhesion molecule (Lutheran blood group) (BCAM), basal cell adhesion molecule (BCAM), basal cell adhesion molecule (Bcam), basal cell adhesion molecule (Lutheran blood group) (Bcam), 1200005K12Rik, AU, B-CAM, cd239, CD239, Gplu, LU, Lu, MGC81012, msk19, MSK19, prr2, zgc:154034Protein level used designations for BCAM
- basal cell adhesion molecule (Lutheran blood group)
- Auberger b antigen
- Lutheran blood group
- basal cell adhesion molecule (Lu and Au blood groups)
- basal cell adhesion molecule
- LU
- basal cell adhesion molecule-like
- B-CAM cell surface glycoprotein
- lutheran antigen
- lutheran glycoprotein
- B-cell adhesion molecule
- F8/G253 antigen
- antigen identified by monoclonal antibody F8
- glycoprotein 95kDa
- Lutheran blood group (Auberger b antigen included)
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