BACE2 抗体
(beta-Site APP-Cleaving Enzyme 2 (BACE2))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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74 results :
BACE2
适用: 小鼠
WB, IHC, IP, ICC
宿主: 兔
Polyclonal
unconjugated
BACE2
适用: 人
WB, IHC, ELISA, IF
宿主: 兔
Polyclonal
unconjugated
BACE2
适用: 人, 大鼠, 小鼠
WB, IHC, ELISA, IHC (p)
宿主: 兔
Polyclonal
unconjugated
BACE2
适用: 人
WB, IHC
宿主: 小鼠
Monoclonal
1-9
unconjugated
Recombinant Antibody
BACE2
适用: 大鼠
ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
BACE2
适用: 人, 大鼠, 小鼠, 豚鼠, Cow, 犬, 马, 猴, Pig, Bat, 小鸡
WB
宿主: 兔
Polyclonal
unconjugated
1 image
BACE2
适用: 人, 大鼠, 小鼠, 豚鼠, Cow, 犬, 马, 兔, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
BACE2
适用: 人, 大鼠, 小鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
BACE2
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
BACE2
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
Latest Publications for our BACE2 抗体
: "BACE-2 is overexpressed in Down's syndrome." in: Experimental neurology, Vol. 182, Issue 2, pp. 335-45, (2003) (PubMed).: "Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 31512-20, (2003) (PubMed).
: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
: "The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region." in: FEBS letters, Vol. 468, Issue 1, pp. 59-64, (2000) (PubMed).
: "Expression analysis of BACE2 in brain and peripheral tissues." in: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20647-51, (2000) (PubMed).
: "BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 17, pp. 9712-7, (2000) (PubMed).
Aliases for BACE2 抗体
beta-site APP-cleaving enzyme 2 (BACE2) 抗体beta-site APP-cleaving enzyme 2 (Bace2) 抗体
1110059C24Rik 抗体
AEPLC 抗体
AI850424 抗体
ALP56 抗体
ARP1 抗体
ASP1 抗体
ASP21 抗体
BAE2 抗体
CDA13 抗体
CEAP1 抗体
DRAP 抗体
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