ASPM 抗体
(Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))
This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011].
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19 results :
ASPM
适用: 人, 大鼠
ELISA, IHC, IF, WB, ICC
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our ASPM 抗体
: "Identification of Abnormal Spindle Microtubule Assembly as a Promising Therapeutic Target for Osteosarcoma." in: Orthopaedic surgery, Vol. 12, Issue 6, pp. 1963-1970, (2021) (PubMed).: "NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells." in: The EMBO journal, Vol. 39, Issue 2, pp. e102378, (2020) (PubMed).
: "Abnormal spindle-like microcephaly-associated protein (ASPM) contributes to the progression of Lung Squamous Cell Carcinoma (LSCC) by regulating CDK4." in: Journal of Cancer, Vol. 11, Issue 18, pp. 5413-5423, (2020) (PubMed).
: "Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity." in: Current biology : CB, Vol. 29, Issue 18, pp. 3072-3080.e5, (2019) (PubMed).
: "Pancreatic cancer survival analysis defines a signature that predicts outcome." in: PLoS ONE, Vol. 13, Issue 8, pp. e0201751, (2018) (PubMed).
: "Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly." in: Scientific reports, Vol. 7, pp. 43708, (2017) (PubMed).
: "Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex." in: Nature cell biology, Vol. 19, Issue 5, pp. 480-492, (2017) (PubMed).
: "Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization." in: Clinical & experimental metastasis, Vol. 29, Issue 5, pp. 397-408, (2012) (PubMed).
: "Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling." in: Nature genetics, Vol. 40, Issue 2, pp. 232-6, (2008) (PubMed).
Aliases for ASPM 抗体
abnormal spindle microtubule assembly (Aspm) 抗体abnormal spindle microtubule assembly (ASPM) 抗体
abnormal spindle microtubule assembly (aspm) 抗体
asp (abnormal spindle)-like, microcephaly associated (Drosophila) (Aspm) 抗体
ASP 抗体
ASPM 抗体
Calmbp1 抗体
D330028K02Rik 抗体
MCPH5 抗体
Sha1 抗体
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