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ASK1 抗体

(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008].

recommended

ASK1 抗体 (pThr845) (ABIN683128)

MAP3K5 适用: 人, 小鼠, 大鼠, Cow ELISA, FACS, IHC (p), WB 宿主: 兔 Polyclonal unconjugated

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recommended

ASK1 抗体 (ABIN969273)

MAP3K5 适用: 人 ICC, FACS, IHC, ELISA, WB 宿主: 小鼠 Monoclonal 2-00E-04 unconjugated

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recommended

ASK1 抗体 (pSer966) (ABIN6255571)

MAP3K5 适用: 人, 小鼠, 大鼠 ELISA, ICC, IF, IHC, WB 宿主: 兔 Polyclonal unconjugated

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ASK1 抗体 by 适用

Find ASK1 抗体 for a variety of species such as anti-Human ASK1, anti-Mouse ASK1, anti-Rat ASK1. The species listed below are among those available. Click on a link to go to the corresponding products.

ASK1 抗体 by 应用范围

Find ASK1 抗体 validated for a specific application such as WB, ELISA, IF (p), IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

ASK1 抗体 by 抗体来源

Find ASK1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

ASK1 抗体 by 抗原表位

Find ASK1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ASK1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal ASK1 抗体. Click on a link to go to the corresponding products.

ASK1 抗体 by 克隆

Find ASK1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

ASK1 抗体 by 标记

Find ASK1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ASK1 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-ASK1 抗体 (pThr845)

Reactivity Cow, Human, Mouse, Rat

Application ELISA, FACS, IHC (p), WB

Validations

Cat. No. ABIN683128

Quantity 100 μL

Datasheet Datasheet

anti-ASK1 抗体

Reactivity Human

Application ICC, FACS, IHC, ELISA, WB

Validations

Cat. No. ABIN969273

Quantity 100 μL

Datasheet Datasheet

anti-ASK1 抗体 (pSer966)

Reactivity Human, Mouse, Rat

Application ELISA, ICC, IF, IHC, WB

Validations

Cat. No. ABIN6255571

Quantity 100 μL

Datasheet Datasheet

anti-ASK1 抗体 (AA 693-933)

Reactivity Mouse

Application ICC, IHC, WB

Validations

Cat. No. ABIN1858085

Quantity 100 μL

Datasheet Datasheet

anti-ASK1 抗体 (AA 1231-1374)

Reactivity Human

Application IF, ELISA, WB

Validations

Cat. No. ABIN517859

Quantity 100 μg

Datasheet Datasheet

anti-ASK1 抗体

Reactivity Human

Application EIA, IF, IHC (p), WB

Validations

Cat. No. ABIN1108200

Quantity 0.1 mL

Datasheet Datasheet

anti-ASK1 抗体 (pSer83)

Reactivity Human

Application ELISA, ICC, IF, IHC, WB

Validations

Cat. No. ABIN6256431

Quantity 100 μL

Datasheet Datasheet

anti-ASK1 抗体 (N-Term)

Reactivity Human, Mouse

Application ELISA, ICC, IF, IHC, WB

Validations

Cat. No. ABIN6260078

Quantity 100 μL

Datasheet Datasheet

anti-ASK1 抗体 (AA 821-849)

Reactivity Human

Application IHC (p), WB

Validations

Cat. No. ABIN6243040

Quantity 400 μL

Datasheet Datasheet

anti-ASK1 抗体 (pSer83)

Reactivity Human

Application IP, IHC, RIA, ELISA, WB

Validations

Cat. No. ABIN95283

Quantity 200 μg

Datasheet Datasheet

anti-ASK1 抗体 (C-Term)

Reactivity Human, Mouse

Application ELISA, ICC, IHC, IHC (p), WB

Validations

Cat. No. ABIN461897

Quantity 0.05 mg

Datasheet Datasheet

anti-ASK1 抗体 (C-Term)

Reactivity Human

Application ELISA, FM, WB

Validations

Cat. No. ABIN6655832

Quantity 100 μg

Datasheet Datasheet

anti-ASK1 抗体 (AA 1231-1374)

Reactivity Human

Application ELISA, WB

Validations

Cat. No. ABIN517858

Quantity 100 μg

Datasheet Datasheet

anti-ASK1 抗体 (Ser966)

Reactivity Human, Mouse

Application IF, IHC (p), WB

Validations

Cat. No. ABIN197326

Quantity 0.1 mL

Datasheet Datasheet

anti-ASK1 抗体 (Ser83)

Reactivity Human

Application IF, IHC (p), WB

Validations

Cat. No. ABIN197310

Quantity 0.1 mL

Datasheet Datasheet

Latest Publications for our ASK1 抗体

Tan, Jin, Wang, Huang, Wu, Ren: "Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells." in: Cells, Vol. 8, Issue 10, (2020) (PubMed).

Yi, Chen, Zhang, Shi, Zhang, Niu, Jia, Cong, Li: "Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways." in: Frontiers in cellular neuroscience, Vol. 13, pp. 190, (2019) (PubMed).

Zhou, Zhang, Hu, Gu, Cai, Wu, Liu, Jiang, Kong, Zhang: "Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 83, (2019) (PubMed).

Feng, Li, Du, Sun, Feng, Li, Liu, Wang, Liu, Amizuka, Li: "Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway." in: Cell death discovery, Vol. 4, pp. 47, (2018) (PubMed).

Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." in: Pancreas, Vol. 44, Issue 2, pp. 331-40, (2015) (PubMed).

Wang, Zhu, Man, Guo, Hao: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." in: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, (2014) (PubMed).

Saha, Jiang, Yang, Zhu, Wang, Schimmer, Qiu, Chang: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).

Nectoux, Fichou, Cagnard, Bahi-Buisson, Nusbaum, Letourneur, Chelly, Bienvenu: "Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy." in: Journal of molecular medicine (Berlin, Germany), Vol. 89, Issue 2, pp. 193-202, (2011) (PubMed).

Pressinotti, Klocker, Schäfer, Luu, Ruschhaupt, Kuner, Steiner, Poustka, Bartsch, Sültmann: "Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer." in: Molecular cancer, Vol. 8, pp. 130, (2010) (PubMed).

Yang, Yu, Guan, Gu, Cao, Wang, Zheng, Xu, Shen, Liu: "ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells." in: Journal of cellular biochemistry, Vol. 110, Issue 3, pp. 581-8, (2010) (PubMed).

Aliases for ASK1 抗体

mitogen-activated protein kinase kinase kinase 5 (MAP3K5) 抗体
mitogen-activated protein kinase kinase kinase 5 (MAPKKK5) 抗体
mitogen-activated protein kinase kinase kinase 5 (Map3k5) 抗体
mitogen-activated protein kinase kinase kinase 5 (map3k5) 抗体
7420452D20Rik 抗体
ASK 抗体
ASK1 抗体
Ask1 抗体
MAPKKK5 抗体
MEKK5 抗体
Mekk5 抗体
mitogen-activated protein kinase kinase kinase 5 抗体
MUD21.11 抗体
MUD21_11 抗体
RGD1306565 抗体

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Aliases for ASK1 抗体

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