ASK1 抗体
(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ASK1 抗体 (AA 1231-1374) | 人 | 小鼠 Monoclonal |
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| ASK1 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| ASK1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ASK1 抗体 (Ser966) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ASK1 抗体 (AA 363-431) (FITC) | 人 | 兔 Polyclonal |
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| ASK1 抗体 (AA 61-90) | 人 | 兔 Polyclonal |
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| ASK1 抗体 (pSer966) (Alexa Fluor 680) | 人, 小鼠, 猴 | 兔 Polyclonal |
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| ASK1 抗体 (pThr838) (Alexa Fluor 680) | 人, 小鼠 | 兔 Polyclonal |
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| ASK1 抗体 (pSer83) (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| ASK1 抗体 (pSer966) (Alexa Fluor 555) | 人, 小鼠, 猴 | 兔 Polyclonal |
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| ASK1 抗体 (pThr838) (Alexa Fluor 555) | 人, 小鼠 | 兔 Polyclonal |
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| ASK1 抗体 (pSer83) (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| ASK1 抗体 (pSer966) (Biotin) | 人, 小鼠, 猴 | 兔 Polyclonal |
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| ASK1 抗体 (pThr838) (Biotin) | 人, 小鼠 | 兔 Polyclonal |
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| ASK1 抗体 (pSer83) (Alexa Fluor 647) | 人 | 兔 Polyclonal |
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| ASK1 抗体 (pSer966) (Alexa Fluor 647) | 人, 小鼠, 猴 | 兔 Polyclonal |
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| ASK1 抗体 (pThr838) (Alexa Fluor 647) | 人, 小鼠 | 兔 Polyclonal |
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| Recombinant ASK1 抗体 (Alexa Fluor 350) | 人, 小鼠 | 兔 Monoclonal |
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| Recombinant ASK1 抗体 (Alexa Fluor 405) | 人, 小鼠 | 兔 Monoclonal |
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| Recombinant ASK1 抗体 (Alexa Fluor 488) | 人, 小鼠 | 兔 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2D11
- 标记
- unconjugated
- 抗体亚型
- IgG Mix lambda
- 抗原表位
- AA 1231-1374
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 1175-1203, C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Ser966
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 363-431
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 61-90
Primary Antibody
- 适用
- 人, 小鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 680
- 抗原表位
- pSer966
Primary Antibody
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 680
- 抗原表位
- pThr838
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 680
- 抗原表位
- pSer83
Primary Antibody
- 适用
- 人, 小鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 555
- 抗原表位
- pSer966
Primary Antibody
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 555
- 抗原表位
- pThr838
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 555
- 抗原表位
- pSer83
Primary Antibody
- 适用
- 人, 小鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗原表位
- pSer966
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 647
- 抗原表位
- pSer83
Primary Antibody
- 适用
- 人, 小鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 647
- 抗原表位
- pSer966
Primary Antibody
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 647
- 抗原表位
- pThr838
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 350
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 405
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Latest Publications for our ASK1 抗体
: "Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells." in: Cells, Vol. 8, Issue 10, (2020) (PubMed).
: "Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways." in: Frontiers in cellular neuroscience, Vol. 13, pp. 190, (2019) (PubMed).
: "Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 83, (2019) (PubMed).
: "Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway." in: Cell death discovery, Vol. 4, pp. 47, (2018) (PubMed).
: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." in: Pancreas, Vol. 44, Issue 2, pp. 331-40, (2015) (PubMed).
: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." in: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, (2014) (PubMed).
: "ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 48, pp. 19691-6, (2012) (PubMed).
: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).
: "Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy." in: Journal of molecular medicine (Berlin, Germany), Vol. 89, Issue 2, pp. 193-202, (2011) (PubMed).
: "Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer." in: Molecular cancer, Vol. 8, pp. 130, (2010) (PubMed).
: "Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways." in: Frontiers in cellular neuroscience, Vol. 13, pp. 190, (2019) (PubMed).
: "Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 83, (2019) (PubMed).
: "Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway." in: Cell death discovery, Vol. 4, pp. 47, (2018) (PubMed).
: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." in: Pancreas, Vol. 44, Issue 2, pp. 331-40, (2015) (PubMed).
: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." in: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, (2014) (PubMed).
: "ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 48, pp. 19691-6, (2012) (PubMed).
: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).
: "Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy." in: Journal of molecular medicine (Berlin, Germany), Vol. 89, Issue 2, pp. 193-202, (2011) (PubMed).
: "Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer." in: Molecular cancer, Vol. 8, pp. 130, (2010) (PubMed).
Aliases for ASK1 抗体
mitogen-activated protein kinase kinase kinase 5 (MAP3K5) 抗体mitogen-activated protein kinase kinase kinase 5 (MAPKKK5) 抗体
mitogen-activated protein kinase kinase kinase 5 (Map3k5) 抗体
mitogen-activated protein kinase kinase kinase 5 (map3k5) 抗体
7420452D20Rik 抗体
ASK 抗体
ASK1 抗体
Ask1 抗体
MAPKKK5 抗体
MEKK5 抗体
Mekk5 抗体
mitogen-activated protein kinase kinase kinase 5 抗体
MUD21.11 抗体
MUD21_11 抗体
RGD1306565 抗体
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