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ASAP2 蛋白

(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2))

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

recommended

ASAP2 Protein (AA 1-1006) (GST tag) (ABIN1345787)

ASAP2 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

ASAP2 Protein (AA 909-1006) (GST tag) (ABIN1345789)

ASAP2 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

ASAP2 Protein (AA 1-1006) (Strep Tag) (ABIN3089284)

Crystallography grade ASAP2 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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ASAP2 蛋白 by Grade

Find ASAP2 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ASAP2 蛋白 by Origin

Find ASAP2 蛋白 for a variety of species such as anti-Human ASAP2, anti-Mouse ASAP2. The species listed below are among those available. Click on a link to go to the corresponding products.

ASAP2 蛋白 by Source

Here you will find ASAP2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ASAP2 蛋白 by 蛋白类型

Here you can find ASAP2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

ASAP2 蛋白 by 应用范围

Find ASAP2 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ASAP2 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ASAP2 Protein (AA 1-1006) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1345787

Quantity 10 μg

Datasheet Datasheet

ASAP2 Protein (AA 909-1006) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1345789

Quantity 10 μg

Datasheet Datasheet

ASAP2 Protein (AA 1-1006) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3089284

Quantity 1 mg

Datasheet Datasheet

ASAP2 Protein (AA 1-958) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3135911

Quantity 1 mg

Datasheet Datasheet

Aliases for ASAP2 蛋白

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2) 蛋白
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 L homeolog (asap2.L) 蛋白
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b (asap1b) 蛋白
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (asap2) 蛋白
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Asap2) 蛋白
6530401G17Rik 蛋白
AMAP2 蛋白
asap2 蛋白
CENTB3 蛋白
DDEF2 蛋白
ddef2 蛋白
Ddef2 蛋白
Gm592 蛋白
Gm1523 蛋白
PAG3 蛋白
PAP 蛋白
Pap-alpha 蛋白
SHAG1 蛋白
si:dkey-37o8.2 蛋白

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ASAP2 蛋白 by Grade

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ASAP2 蛋白 by 应用范围

Popular ASAP2 蛋白

Aliases for ASAP2 蛋白

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