ASAH2 蛋白
(N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008].
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Aliases for ASAH2 蛋白
N-acylsphingosine amidohydrolase 2 (ASAH2) 蛋白N-acylsphingosine amidohydrolase 2 (Asah2) 蛋白
AI585898 蛋白
BCDase 蛋白
HNAC1 蛋白
LCDase 蛋白
N-CDase 蛋白
NCDase 蛋白
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