This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq, Jul 2008].
Latest Publications for our Aryl Hydrocarbon Receptor 蛋白
Saito, Miki, Hata, Takagi, Iida, Oba, Ono, Ishida, Suzuki, Ohuchi, Sasano: "Aryl hydrocarbon receptor in breast cancer—a newly defined prognostic marker." in: Hormones & cancer, Vol. 5, Issue 1, pp. 11-21, (2014) (PubMed).
van den Bogaard, Bergboer, Vonk-Bergers, van Vlijmen-Willems, Hato, van der Valk, Schröder, Joosten, Zeeuwen, Schalkwijk: "Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis." in: The Journal of clinical investigation, Vol. 123, Issue 2, pp. 917-27, (2013) (PubMed).