ARHGEF18 抗体
(rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
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Latest Publications for our ARHGEF18 抗体
: "Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly." in: Cell reports, Vol. 32, Issue 3, pp. 107924, (2020) (PubMed).: "VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism." in: The Journal of cell biology, Vol. 218, Issue 5, pp. 1725-1742, (2019) (PubMed).
: "Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs." in: eLife, Vol. 7, (2018) (PubMed).
: "Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration." in: The Journal of cell biology, Vol. 216, Issue 6, pp. 1543-1556, (2017) (PubMed).
: "An apical MRCK-driven morphogenetic pathway controls epithelial polarity." in: Nature cell biology, Vol. 19, Issue 9, pp. 1049-1060, (2017) (PubMed).
: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).
: "Expression of p114RhoGEF predicts lymph node metastasis and poor survival of squamous-cell lung carcinoma patients." in: Tumour biology, Vol. 34, Issue 3, pp. 1925-33, (2013) (PubMed).
: "ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation." in: Development (Cambridge, England), Vol. 140, Issue 13, pp. 2787-97, (2013) (PubMed).
: "Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion." in: PLoS ONE, Vol. 7, Issue 11, pp. e50188, (2012) (PubMed).
: "Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis." in: Nature cell biology, Vol. 13, Issue 2, pp. 159-66, (2011) (PubMed).
Aliases for ARHGEF18 抗体
rho/rac guanine nucleotide exchange factor (GEF) 18a (arhgef18a) 抗体Rho/Rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18) 抗体
Rho/Rac guanine nucleotide exchange factor 18 (ARHGEF18) 抗体
rho guanine nucleotide exchange factor 18 (LOC100027283) 抗体
rho/rac guanine nucleotide exchange factor (GEF) 18 (Arhgef18) 抗体
Rho/Rac guanine nucleotide exchange factor 18 (Arhgef18) 抗体
AI467246 抗体
arhgef18 抗体
D030053O22Rik 抗体
P114-RhoGEF 抗体
wu:fc21e04 抗体
wu:fj05f11 抗体
zgc:85686 抗体
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