This gene is a member of the ARID (AT-rich interaction domain) family of proteins. The ARID domain is a helix-turn-helix motif-based DNA-binding domain. ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008].
Wilsker, Patsialou, Dallas, Moran: "ARID proteins: a diverse family of DNA binding proteins implicated in the control of cell growth, differentiation, and development." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 13, Issue 3, pp. 95-106, (2002) (PubMed).