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APOB 产品

(Apolipoprotein B (APOB))

Categories

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008].

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Featured APOB Categories

APOB 抗体

High quality antibodies with extensive validation data.

APOB ELISA试剂盒

Reliable ELISA kits for a wide range of species.

APOB 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended APOB 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (10)
Cat. No. ABIN7429130
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7426895
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN5663872
Quantity 100 μL
Datasheet Datasheet

Recommended APOB ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (5)
Cat. No. ABIN6730915
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
  • (1)
Cat. No. ABIN612664
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963642
Quantity 96 tests
Datasheet Datasheet

Recommended APOB 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121865
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121866
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345338
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our APOB Products

Tomassen, Govers, Vos, de Wit: "Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model." in: Lipids in health and disease, Vol. 22, Issue 1, pp. 4, (2023) (PubMed).

Matsumoto, Takahashi, Chang, Wu, Yamamoto, Ishihama, Takakura: "Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance." in: Journal of extracellular vesicles, Vol. 9, Issue 1, pp. 1696517, (2020) (PubMed).

Emmer, Lascuna, Tang, Kotnik, Saunders, Khoriaty, Ginsburg: "Murine Surf4 is essential for early embryonic development." in: PLoS ONE, Vol. 15, Issue 1, pp. e0227450, (2020) (PubMed).

Morishita, Zhao, Tamura, Nishimura, Kanda, Sakamaki, Okazaki, Li, Mizushima: "A critical role of VMP1 in lipoprotein secretion." in: eLife, Vol. 8, (2020) (PubMed).

Lin, Liddle, Neizer, Robinson, Wright: "Acute whole apple consumption did not influence postprandial lipaemia: a randomised crossover trial." in: The British journal of nutrition, Vol. 123, Issue 7, pp. 807-817, (2020) (PubMed).

Yu, Rimbert, Palmer, Toyohara, Xia, Xia, Ferreira, Chen, Chen, Loaiza, Horwitz, Kacergis, Zhao, Soukas, Kuivenhoven, Kathiresan, Cowan: "GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis." in: Cell, Vol. 179, Issue 6, pp. 1276-1288.e14, (2020) (PubMed).

Ganesan, Sinniah, Chik, Alshawsh: "Punicalagin Regulates Apoptosis-Autophagy Switch via Modulation of Annexin A1 in Colorectal Cancer." in: Nutrients, Vol. 12, Issue 8, (2020) (PubMed).

Carnevale, Pastori, Nocella, Cammisotto, Bartimoccia, Novo, Del Ben, Farcomeni, Angelico, Violi: "Gut-derived lipopolysaccharides increase post-prandial oxidative stress via Nox2 activation in patients with impaired fasting glucose tolerance: effect of extra-virgin olive oil." in: European journal of nutrition, Vol. 58, Issue 2, pp. 843-851, (2019) (PubMed).

Sołtysik, Ohsaki, Tatematsu, Cheng, Fujimoto: "Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis." in: Nature communications, Vol. 10, Issue 1, pp. 473, (2019) (PubMed).

Lu, Yuan, Wang, Zhang, Yuan, Wu, Zhou, He, Lu, Chen, Fan, Liang, Cheng: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." in: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).

Synonyms and alternative names related to APOB

apolipoprotein B (APOB), apolipoprotein B (Apob), Ac1-060, AI315052, APOB, ApoB(100), ApoB-48, apob-48, Apo B-100, ApoB-100, apob-100, APOB-100, FLDB, LDLCQ4

Protein level used designations for APOB

  • apo B-100
  • apoB-100
  • apoB-48
  • apolipoprotein B (including Ag(x) antigen)
  • apolipoprotein B-100
  • apolipoprotein B48
  • mutant Apo B 100
  • apolipoprotein B PI
  • apolipoprotein B-48
  • apolipoprotein B
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