APH1B 产品
(Anterior Pharynx Defective 1 Homolog B (Aph1b))
Categories
This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011].
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Featured APH1B Categories
Recommended APH1B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
- (1)
Cat. No.
ABIN1386275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7139847
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN1392469
Quantity
100 μL
Datasheet
Datasheet
Recommended APH1B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6976100
Quantity
96 tests
Datasheet
Datasheet
Recommended APH1B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3104477
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3125756
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our APH1B Products
: "Nicastrin is required for APP but not Notch processing, while Aph-1 is dispensable for processing of both APP and Notch." in: Journal of neurochemistry, (2015) (PubMed).: "Impact of the cellular prion protein on amyloid-? and 3PO-tau processing." in: Journal of Alzheimer's disease : JAD, Vol. 38, Issue 3, pp. 551-65, (2013) (PubMed).
Synonyms and alternative names related to APH1B
aph-1 homolog B, gamma-secretase subunit (APH1B), aph-1 homolog B, gamma secretase subunit (Aph1b), aph1 homolog B, gamma secretase subunit (Aph1b), 2310057K14Rik, APH-1B, APH-1B', Aph1c, PRO1328, PSFL, TAAV688Protein level used designations for APH1B
- anterior pharynx defective 1 homolog B
- aph-1beta
- gamma-secretase subunit APH-1B
- anterior pharynx defective 1b homolog
- APH-1b
- APH1B homolog
- anterior pharynx defective 1c homolog
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