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APEH 产品

(N-Acylaminoacyl-Peptide Hydrolase (APEH))
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008].

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Featured APEH Categories

APEH 抗体

High quality antibodies with extensive validation data.

APEH ELISA试剂盒

Reliable ELISA kits for a wide range of species.

APEH 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended APEH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN7143250
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN2783264
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238171
Quantity 200 μL
Datasheet Datasheet

Recommended APEH ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968772
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975488
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1120486
Quantity 96 tests
Datasheet Datasheet

Recommended APEH 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345303
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088549
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126598
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our APEH Products

Santhoshkumar, Xie, Raju, Reneker, Sharma: "Lens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase." in: The Journal of biological chemistry, Vol. 289, Issue 13, pp. 9039-52, (2014) (PubMed).

Edosada, Quan, Wiesmann, Tran, Sutherlin, Reynolds, Elliott, Raab, Fairbrother, Wolf: "Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity." in: The Journal of biological chemistry, Vol. 281, Issue 11, pp. 7437-44, (2006) (PubMed).

Synonyms and alternative names related to APEH

acylaminoacyl-peptide hydrolase (APEH), acylaminoacyl-peptide hydrolase (Apeh), acylpeptide hydrolase (Apeh), acylaminoacyl-peptide hydrolase (apeh), AAP, AARE, ACPH, APH, cb5, D3F15S2, D3S48E, DNF15S2, OPH, sb:cb5, wu:fi37d02

Protein level used designations for APEH

  • N-acylaminoacyl-peptide hydrolase
  • acyl-peptide hydrolase
  • acylamino-acid-releasing enzyme
  • acylaminoacyl-peptidase
  • oxidized protein hydrolase
  • AARE
  • APH
  • acylpeptide hydrolase
  • N-acylpeptide hydrolase
  • acylamino acid-releasing enzyme
  • acylaminoacyl peptidase
  • N-acylaminoacyl peptide hydrolase
  • Acyl-peptide hydrolase
  • Acylaminoacyl-peptidase
  • LOW QUALITY PROTEIN: acylamino-acid-releasing enzyme
  • acylamino-acid-releasing enzyme-like
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