(Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3))
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008].
McLoughlin, Irving, Brownlees, Brion, Leroy, Miller: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." in: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).
Borg, Straight, Kaech, de Taddéo-Borg, Kroon, Karnak, Turner, Kim, Margolis: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).
Borg, Yang, De Taddéo-Borg, Margolis, Turner: "The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion." in: The Journal of biological chemistry, Vol. 273, Issue 24, pp. 14761-6, (1998) (PubMed).
Aliases for APBA3 抗体
amyloid beta precursor protein binding family A member 3 (APBA3) 抗体 amyloid beta (A4) precursor protein-binding, family A, member 3 (Apba3) 抗体 amyloid beta precursor protein binding family A member 3 (Apba3) 抗体 AW208791 抗体 lin-10 抗体 MGC:15815 抗体 Mint-3 抗体 mint3 抗体 Mint3 抗体 X11gamma 抗体 X11L2 抗体