YAP1 抗体
Quick Overview for YAP1 抗体 (ABIN969574)
抗原
See all YAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- YAP1 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human YAP1 expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).
: "YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway." in: Nature cell biology, Vol. 11, Issue 12, pp. 1444-50, (2009) (PubMed).
-
: "YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).
-
- YAP1 (Yes-Associated Protein 1 (YAP1))
-
别名
- YAP1
-
背景
- This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
-
UniProt
- P46937
-
途径
- MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
-