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YAP1 抗体

This anti-YAP1 antibody is a 小鼠 单克隆 antibody detecting YAP1 in WB, ELISA, IHC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969574
发货至: 中国

Quick Overview for YAP1 抗体 (ABIN969574)

抗原

See all YAP1 抗体
YAP1 (Yes-Associated Protein 1 (YAP1))

适用

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宿主

  • 131
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小鼠

克隆类型

  • 113
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  • 2
单克隆

标记

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This YAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

1A12
  • 原理

    YAP1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human YAP1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Fernandez-L, Northcott, Dalton, Fraga, Ellison, Angers, Taylor, Kenney: "YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).

    Zhang, Ji, Yu, Overholtzer, Smolen, Wang, Brugge, Dyson, Haber: "YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway." in: Nature cell biology, Vol. 11, Issue 12, pp. 1444-50, (2009) (PubMed).

  • 抗原

    YAP1 (Yes-Associated Protein 1 (YAP1))

    别名

    YAP1

    背景

    This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.

    UniProt

    P46937

    途径

    MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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