TGFB1 抗体
Quick Overview for TGFB1 抗体 (ABIN969435)
抗原
See all TGFB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TGF beta1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of TGF beta1 expressed in E. Coli.
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亚型
- IgG2a
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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TGFbeta pathobiology in the eye." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 86, Issue 2, pp. 106-15, (2006) (PubMed).
: "TGFbeta1 regulates the inflammatory response during chronic neurodegeneration." in: Neurobiology of disease, Vol. 22, Issue 3, pp. 638-50, (2006) (PubMed).
: "
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TGFbeta pathobiology in the eye." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 86, Issue 2, pp. 106-15, (2006) (PubMed).
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- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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别名
- TGF beta1
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背景
- TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.
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UniProt
- P01137
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途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
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