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PTH1R 抗体

This anti-PTH1R antibody is a 小鼠 单克隆 antibody detecting PTH1R in IHC, ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969372
发货至: 中国

Quick Overview for PTH1R 抗体 (ABIN969372)

抗原

See all PTH1R 抗体
PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

适用

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宿主

  • 42
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小鼠

克隆类型

  • 41
  • 10
单克隆

标记

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This PTH1R antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

克隆位点

4D2
  • 原理

    PTH1R Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human PTH1R expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Dean, Vilardaga, Potts, Gardella: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).

    Yang, Hoang, Kubo, Kawano, Chou, Sowers, Huvos, Meyers, Healey, Gorlick: "Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 121, Issue 5, pp. 943-54, (2007) (PubMed).

  • 抗原

    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

    别名

    PTH1R

    背景

    The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

    分子量

    66 kDa

    基因ID

    5745

    UniProt

    Q03431

    途径

    Regulation of Carbohydrate Metabolic Process
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