PTH1R 抗体
Quick Overview for PTH1R 抗体 (ABIN969372)
抗原
See all PTH1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PTH1R Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human PTH1R expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).
: "Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 121, Issue 5, pp. 943-54, (2007) (PubMed).
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: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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别名
- PTH1R
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背景
- The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
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分子量
- 66 kDa
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基因ID
- 5745
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UniProt
- Q03431
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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