PTH1R 抗体 (C-Term)
(3 references)-
- 抗原 See all PTH1R 抗体
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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抗原表位
- AA 388-406, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTH1R antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Parathyroid hormone/parathyroid hormone-related peptide receptor(PTH1R) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- KLRETNAGRC DTRQQYRKL
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Parathyroid hormone/parathyroid hormone-related peptide receptor(PTH1R) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: parathyroid hormone 1 receptor
Protein Name: Parathyroid hormone/parathyroid hormone-related peptide receptor - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Parathyroid Hormone Receptor 1(388-406aa KLRETNAGRCDTRQQYRKL), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product PTH1R Primary Antibody
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anti-Parathyroid Hormone 1 Receptor (PTH1R) (pThr1) antibody
PTH1R 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 1268-1341) antibodyPTH1R 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) antibodyPTH1R 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (1st Extracellular Loop), (AA 241-255) antibodyPTH1R 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 485-593) antibodyPTH1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (N-Term) antibodyPTH1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 146-169) antibodyPTH1R 适用: 人, 小鼠, Cow, Pig, 犬, 猴, 马 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).
: "Effects of Intermittent Administration of Parathyroid Hormone (1-34) on Bone Differentiation in Stromal Precursor Antigen-1 Positive Human Periodontal Ligament Stem Cells." in: Stem cells international, Vol. 2016, pp. 4027542, (2016) (PubMed).
: "TGF-? Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma." in: Journal of Cancer, Vol. 6, Issue 6, pp. 511-8, (2015) (PubMed).
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: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).
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- 抗原
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- 别名
- PTH1R (PTH1R 产品)
- 别名
- PFE antibody, PTHR antibody, PTHR1 antibody, PPR antibody, Pthr antibody, Pthr1 antibody, pthr1 antibody, zPTH1R antibody, PTHrel antibody, PTH1 antibody, PTH antibody, parathyroid hormone 1 receptor antibody, parathyroid hormone 1 receptor a antibody, PTH1R antibody, Pth1r antibody, pth1ra antibody
- 背景
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Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.
Synonyms: MGC138426 antibody|MGC138452 antibody|Parathyroid hormone 1 receptor antibody|Parathyroid hormone/parathyroid hormone related peptide receptor antibody|Parathyroid hormone/parathyroid hormone related protein receptor antibody|Parathyroid hormone/parathyroid hormone-related peptide receptor antibody|PTH receptor antibody|PTH/PTHr receptor antibody|PTH/PTHrP receptor antibody|PTH/PTHrP type I receptor antibody|PTH1 receptor antibody|PTH1R antibody|PTH1R_HUMAN antibody|PTHR 1 antibody|PTHR antibody|PTHR1 antibody - UniProt
- Q03431
- 途径
- Regulation of Carbohydrate Metabolic Process
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