PPARG 抗体 (AA 170-270)
Quick Overview for PPARG 抗体 (AA 170-270) (ABIN969358)
抗原
See all PPARG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 170-270
-
原理
- PPARG Antibody
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of PPARG (aa170-270) expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
- ELISA: 1/10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Association of PPARG2 Pro12Ala variant with larger body mass index in Mestizo and Amerindian populations of Mexico. ..." in: Human biology, Vol. 79, Issue 1, pp. 111-9, (2007) (PubMed).
: "Depressed peroxisome proliferator-activated receptor gamma (PPargamma) is indicative of severe pulmonary sarcoidosis: possible involvement of interferon gamma (IFN-gamma)." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 23, Issue 2, pp. 93-100, (2007) (PubMed).
-
: "Association of PPARG2 Pro12Ala variant with larger body mass index in Mestizo and Amerindian populations of Mexico. ..." in: Human biology, Vol. 79, Issue 1, pp. 111-9, (2007) (PubMed).
-
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
-
别名
- PPARG
-
背景
- PPARG: peroxisome proliferator-activated receptor gamma. This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
-
基因ID
- 5468
-
UniProt
- P37231
-
途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
-