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PARL 抗体 (AA 112-167)

This anti-PARL antibody is a 小鼠 单克隆 antibody detecting PARL in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969340
发货至: 中国

Quick Overview for PARL 抗体 (AA 112-167) (ABIN969340)

抗原

See all PARL 抗体
PARL (Presenilin Associated, Rhomboid-Like (PARL))

适用

  • 23
  • 10
  • 9
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  • 2
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  • 2
  • 2
  • 1
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宿主

  • 19
  • 3
  • 2
小鼠

克隆类型

  • 21
  • 3
单克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
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  • 1
This PARL antibody is un-conjugated

应用范围

  • 14
  • 10
  • 9
  • 2
  • 2
  • 1
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  • 1
ELISA

克隆位点

8C4B2
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 112-167

    原理

    PARL Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • McQuibban, Saurya, Freeman: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).

    Pellegrini, Passer, Canelles, Lefterov, Ganjei, Fowlkes, Koonin, DAdamio: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).

  • 抗原

    PARL (Presenilin Associated, Rhomboid-Like (PARL))

    别名

    PARL

    背景

    PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

    基因ID

    55486

    UniProt

    Q9H300

    途径

    Autophagy
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