PARL 抗体 (N-Term)
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北京 101111
Quick Overview for PARL 抗体 (N-Term) (ABIN2782038)
抗原
See all PARL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PARL Antibody - N-terminal region
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序列
- SLIKPLFFTV GFTGCAFGSA AIWQYESLKS RVQSYFDGIK ADWLDSIRPQ
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PARL. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PARL
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anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibody
PARL 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 112-167) antibodyPARL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8C4B2 unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 97-146) antibodyPARL 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 1-170) antibodyPARL 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 1-170) antibodyPARL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 2-100) antibodyPARL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibodyPARL 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibodyPARL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108894
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 11, pp. 1658-65, (2013) (PubMed).
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- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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别名
- PARL
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背景
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Background Information: PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: Presenilin associated, rhomboid-like
Alternative Symbols: PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2
Protein Name: Presenilins-associated rhomboid-like protein, mitochondrial
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分子量
- 36kDa
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基因ID
- 55486
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NCBI登录号
- NP_001032728
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UniProt
- Q9H300
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途径
- Autophagy
抗原
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