MERTK 抗体
Quick Overview for MERTK 抗体 (ABIN969283)
抗原
See all MERTK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MER Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of MER expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye." in: The Proceedings of the Nutrition Society, Vol. 64, Issue 4, pp. 434-50, (2005) (PubMed).
: "First-line therapy with gemcitabine and paclitaxel in locally, recurrent or metastatic breast cancer: a phase II study." in: BMC cancer, Vol. 5, pp. 151, (2005) (PubMed).
: "Techniques for delivery of arachidonic acid to Pacific oyster, Crassostrea gigas, spat." in: Lipids, Vol. 40, Issue 9, pp. 931-9, (2005) (PubMed).
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: "Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye." in: The Proceedings of the Nutrition Society, Vol. 64, Issue 4, pp. 434-50, (2005) (PubMed).
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- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
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别名
- MER
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背景
- MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
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UniProt
- Q12866
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途径
- RTK signaling
抗原
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