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MDM4-binding Protein 抗体

Cited in 2+ publications. This anti-MDM4-binding Protein antibody is a 小鼠 单克隆 antibody detecting MDM4-binding Protein in ELISA, IHC 和 ICC. Suitable for 人.
产品编号 ABIN969282
发货至: 中国
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Quick Overview for MDM4-binding Protein 抗体 (ABIN969282)

抗原

See all MDM4-binding Protein (MDM4) 抗体
MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

适用

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宿主

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小鼠

克隆类型

  • 64
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单克隆

标记

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This MDM4-binding Protein antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

2D10F4
  • 原理

    MDM4 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human MDM4 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Pan, Chen: "Modification of MDMX by sumoylation." in: Biochemical and biophysical research communications, Vol. 332, Issue 3, pp. 702-9, (2005) (PubMed).

    Wunderlich, Ghosh, Weghorst, Berberich: "MdmX represses E2F1 transactivation." in: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 4, pp. 472-8, (2004) (PubMed).

  • 抗原

    MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

    别名

    MDM4

    背景

    MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.

    分子量

    55 kDa

    基因ID

    4194

    UniProt

    O15151

    途径

    Cell Division Cycle
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