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ITK 抗体

Name: ITK 抗体
Brand: antibodies-online
SKU: ABIN969222
Availability: OutOfStock

This anti-ITK antibody is a 小鼠单克隆 antibody detecting ITK in WB, ELISA, ICC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis using ITK mouse mAb against Jurkat cell lysate. (ITK 抗体)

Flow cytometric analysis of Jurkat cells using ITK mouse mAb (blue) and negative control (red). (ITK 抗体)

FACS

Immunofluorescence analysis of Jurkat cells using ITK mouse mAb (green). (ITK 抗体)

Western blot analysis using ITK mAb against human ITK (AA: 2-120) recombinant protein. (ITK 抗体)

Red: Control Antigen (100 ng), Purple: Antigen (10 ng), Green: Antigen (50 ng), Blue: Antigen (100 ng), (ITK 抗体)

ELISA

5 images

(2 references)

产品编号 ABIN969222

发货至: 中国

Datasheet as PDF

Quick Overview for ITK 抗体 (ABIN969222)

抗原

See all ITK 抗体

ITK (IL2-Inducible T-Cell Kinase (ITK))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This ITK antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

5G6

Discover our top product ITK Primary Antibody

原理

ITK Antibody

纯化方法

Ascitic fluid

免疫原

Purified recombinant fragment of human ITK expressed in E. Coli.

亚型

IgG1
anti-IL2-Inducible T-Cell Kinase (ITK) (Internal Region) antibody
Verified ITK 适用: 人, 大鼠 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) (C-Term) antibody
Verified ITK 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) (AA 2-110) antibody
ITK 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5G12C4 unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) (pTyr512) antibody
ITK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) (AA 368-625) antibody
ITK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) antibody
ITK 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 8F10 unconjugated Recombinant Antibody

anti-IL2-Inducible T-Cell Kinase (ITK) (AA 228-262) antibody
ITK 适用: 人 WB 宿主: 兔 Polyclonal RB50773 unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) (AA 1-111) antibody
ITK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) antibody
ITK 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-IL2-Inducible T-Cell Kinase (ITK) (AA 156-190), (N-Term) antibody
ITK 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50676 unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

限制

仅限研究用
状态

Liquid

缓冲液

Ascitic fluid containing 0.03 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).
抗原

ITK (IL2-Inducible T-Cell Kinase (ITK))

别名

ITK

背景

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

分子量

72 kDa

UniProt

Q08881

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway