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ITK 抗体

This anti-ITK antibody is a 小鼠 单克隆 antibody detecting ITK in WB, ELISA, ICC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969222
发货至: 中国

Quick Overview for ITK 抗体 (ABIN969222)

抗原

See all ITK 抗体
ITK (IL2-Inducible T-Cell Kinase (ITK))

适用

  • 49
  • 22
  • 12
  • 6
  • 3

宿主

  • 65
  • 4
  • 2
小鼠

克隆类型

  • 64
  • 7
单克隆

标记

  • 35
  • 8
  • 4
  • 3
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITK antibody is un-conjugated

应用范围

  • 42
  • 34
  • 17
  • 14
  • 14
  • 9
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

5G6
  • 原理

    ITK Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ITK expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

    Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).

  • 抗原

    ITK (IL2-Inducible T-Cell Kinase (ITK))

    别名

    ITK

    背景

    This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    分子量

    72 kDa

    UniProt

    Q08881

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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