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FLT1 抗体

This anti-FLT1 antibody is a 小鼠 单克隆 antibody detecting FLT1 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969146
发货至: 中国

Quick Overview for FLT1 抗体 (ABIN969146)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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宿主

  • 142
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小鼠

克隆类型

  • 140
  • 55
单克隆

标记

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This FLT1 antibody is un-conjugated

应用范围

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ELISA

克隆位点

3D10
  • 原理

    FLT1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Man, Yang, Cai, Yao, Zheng: "Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis." in: Molecular medicine (Cambridge, Mass.), Vol. 12, Issue 7-8, pp. 127-36, (2006) (PubMed).

    Flick, Sapi, Perrotta, Maher, Halaban, Carter, Kacinski: "Recognition of activated CSF-1 receptor in breast carcinomas by a tyrosine 723 phosphospecific antibody." in: Oncogene, Vol. 14, Issue 21, pp. 2553-61, (1997) (PubMed).

  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    FLT1

    背景

    Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), also known as FLT1 or VEGFR-1. It is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

    分子量

    100 kDa

    基因ID

    2321

    UniProt

    P17948

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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