FGFR4 抗体
(2 references)Quick Overview for FGFR4 抗体 (ABIN969139)
抗原
See all FGFR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FGFR4 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of FGFR4 expressed in E. Coli.
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亚型
- IgG1
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anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibody
FGFR4 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A1G2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibodyFGFR4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3B5B8 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibodyFGFR4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB38171 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55) antibodyFGFR4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 31-145) antibodyFGFR4 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 1-100) antibodyFGFR4 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 168-369) antibodyFGFR4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 25-182) antibodyFGFR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibody (PE)FGFR4 适用: 人 FACS 宿主: 小鼠 Monoclonal 4FR6D3 PE
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Targeting N-cadherin through fibroblast growth factor receptor-4: distinct pathogenetic and therapeutic implications." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2965-75, (2006) (PubMed).
: "Telling the liver (not) to make bile acids: a new voice from the gut?" in: Cell metabolism, Vol. 2, Issue 4, pp. 209-10, (2005) (PubMed).
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: "Targeting N-cadherin through fibroblast growth factor receptor-4: distinct pathogenetic and therapeutic implications." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2965-75, (2006) (PubMed).
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- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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别名
- FGFR4
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背景
- FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.
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分子量
- 88 kDa
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基因ID
- 2264
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UniProt
- P22455
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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