FAK 抗体
(2 references)Quick Overview for FAK 抗体 (ABIN969129)
抗原
See all FAK (PTK2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FAK Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human FAK expressed in E. Coli.
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亚型
- IgG1
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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr397) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 700-800) antibodyPTK2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 798-1041) antibodyPTK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 355-490) antibodyPTK2 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr576) antibodyPTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 396-423) antibodyPTK2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20775 unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (C-Term) antibodyPTK2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 1-680) antibodyPTK2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr861) antibodyPTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibodyPTK2 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10H7 unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 22865-77, (2009) (PubMed).
: "Targeting of the protein interaction site between FAK and IGF-1R." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 301-5, (2009) (PubMed).
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: "B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 22865-77, (2009) (PubMed).
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- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
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别名
- FAK
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背景
- This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a
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分子量
- 119 kDa
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基因ID
- 5747
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UniProt
- Q05397
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途径
- Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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