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MAPK6 抗体

Cited in 2+ publications. This 小鼠 单克隆 anti-MAPK6 antibody (Clone 4E8) specifically detects MAPK6 in ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN969115
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAPK6 抗体 (ABIN969115)

抗原

See all MAPK6 抗体
MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MAPK6 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

4E8
  • 原理

    ERK3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ERK3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Klinger, Turgeon, Lévesque, Wood, Aagaard-Tillery, Meloche: "Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 39, pp. 16710-5, (2009) (PubMed).

    Déléris, Rousseau, Coulombe, Rodier, Tanguay, Meloche: "Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5." in: Journal of cellular physiology, Vol. 217, Issue 3, pp. 778-88, (2008) (PubMed).

  • 抗原

    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

    别名

    ERK3

    背景

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts

    分子量

    105 kDa

    基因ID

    5597

    UniProt

    Q16659

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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