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MAPK6 抗体 (pSer189)

MAPK6 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB5800 unconjugated
产品编号 ABIN6241031
发货至: 中国
  • 抗原 See all MAPK6 抗体
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    抗原表位
    • 16
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer189
    适用
    • 55
    • 46
    • 27
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 62
    • 5
    • 3
    • 1
    克隆类型
    • 67
    • 4
    多克隆
    标记
    • 38
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK6 antibody is un-conjugated
    应用范围
    • 51
    • 35
    • 18
    • 14
    • 13
    • 11
    • 8
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    C, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Phospho-ERK3-S189 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S189 of human ERK3.
    克隆位点
    RB5800
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAPK6 Primary Antibody
  • 应用备注
    IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Wang, Kong, Lin, Li, Izumiya, Ding, Zhang, Hu, Yang, Gao, Lam, Li: "A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer." in: Acta pharmacologica Sinica, Vol. 38, Issue 6, pp. 931-942, (2018) (PubMed).

    Perander, Al-Mahdi, Jensen, Nunn, Kildalsen, Johansen, Gabrielsen, Keyse, Seternes: "Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2." in: Scientific reports, Vol. 7, pp. 43471, (2017) (PubMed).

    De la Mota-Peynado, Chernoff, Beeser: "Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13603-11, (2011) (PubMed).

    Purcell, Wilkins, York, Saba-El-Leil, Meloche, Robbins, Molkentin: "Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 35, pp. 14074-9, (2007) (PubMed).

    Sakai, Yamauchi, Kawano: "[Measurement of internal voids in impression material using a digital image analyzer. Part 1. Investigation of the measurement system of a digital image analyzer]." in: Nihon Hotetsu Shika Gakkai zasshi, Vol. 32, Issue 1, pp. 28-36, (1989) (PubMed).

  • 抗原
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    别名
    ERK3 (MAPK6 产品)
    别名
    ERK3 antibody, HsT17250 antibody, PRKM6 antibody, p97MAPK antibody, 2610021I23Rik antibody, D130053K17Rik antibody, Erk3 antibody, Mapk4 antibody, Mapk63 antibody, Prkm4 antibody, Prkm6 antibody, ATMAPK6 antibody, ATMPK6 antibody, F18O19.10 antibody, MAP KINASE 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, SUSERK3 antibody, erk3 antibody, p97mapk antibody, si:ch211-235f12.1 antibody, mitogen-activated protein kinase 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, Mapk6 antibody, MPK6 antibody, mapk6 antibody
    背景
    ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
    分子量
    82681
    NCBI登录号
    NP_002739
    UniProt
    Q16659
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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