p300 抗体
Quick Overview for p300 抗体 (ABIN969098)
抗原
See all p300 (EP300) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            原理
- EP300 Antibody
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                                            纯化方法
- Ascitic fluid
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                                            免疫原
- Purified recombinant fragment of EP300 expressed in E. Coli.
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                                            亚型
- IgG1
 
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                                            应用备注
- ELISA: 1/10000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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    - 
                                            : "The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB."    in: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008)         (PubMed).        
 : "p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9678-87, (2007) (PubMed).
 
 
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                                            : "The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB."    in: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008)         (PubMed).        
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    - p300 (EP300) (E1A Binding Protein P300 (EP300))
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                                            别名
- EP300
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                                            背景
- EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
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                                            UniProt
- Q09472
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                                            途径
- p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
 抗原
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