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Calnexin 抗体

This anti-Calnexin antibody is a 小鼠 单克隆 antibody detecting Calnexin in WB, ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969000
发货至: 中国

Quick Overview for Calnexin 抗体 (ABIN969000)

抗原

See all Calnexin (CANX) 抗体
Calnexin (CANX)

适用

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宿主

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小鼠

克隆类型

  • 122
  • 54
单克隆

标记

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This Calnexin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

3H4A7
  • 原理

    Calnexin Antibody

    序列

    CEAAEERPWL WVVYILTVAL

    纯化方法

    Ascitic fluid

    免疫原

    Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Orlando: "The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." in: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).

    Egan, Pearson, Weiner, Rajendran, Rubin, Glöckner-Pagel, Canny, Du, Lukacs, Caplan: "Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 600-2, (2004) (PubMed).

    Oda, Hosokawa, Wada, Nagata: "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1394-7, (2003) (PubMed).

  • 抗原

    Calnexin (CANX)

    别名

    Calnexin

    背景

    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

    分子量

    90 kDa

    基因ID

    821

    UniProt

    P27824

    途径

    MAPK Pathway, Thyroid Hormone Synthesis
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