Calnexin 抗体
Quick Overview for Calnexin 抗体 (ABIN969000)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Calnexin Antibody
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序列
- CEAAEERPWL WVVYILTVAL
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纯化方法
- Ascitic fluid
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免疫原
- Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.
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亚型
- IgG2b
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." in: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).
: "Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 600-2, (2004) (PubMed).
: "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1394-7, (2003) (PubMed).
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: "The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." in: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).
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- Calnexin (CANX)
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别名
- Calnexin
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背景
- This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
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分子量
- 90 kDa
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基因ID
- 821
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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