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BID 抗体

This anti-BID antibody is a 小鼠 单克隆 antibody detecting BID in WB, IHC, ELISA, FACS 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN968979
发货至: 中国

Quick Overview for BID 抗体 (ABIN968979)

抗原

See all BID 抗体
BID (BH3 Interacting Domain Death Agonist (BID))

适用

  • 141
  • 75
  • 38
  • 2
  • 2
  • 1

宿主

  • 157
  • 22
  • 1
  • 1
小鼠

克隆类型

  • 149
  • 32
单克隆

标记

  • 93
  • 17
  • 15
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This BID antibody is un-conjugated

应用范围

  • 151
  • 70
  • 56
  • 38
  • 27
  • 26
  • 26
  • 25
  • 22
  • 20
  • 7
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

3C5
  • 原理

    BID Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant full length protein of human BID expressed in E. Coli

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wan, Liu, Xing, Chen: "Bid is required in NPe6-PDT-induced apoptosis." in: Photochemistry and photobiology, Vol. 84, Issue 1, pp. 250-7, (2008) (PubMed).

    Wu, Xing, Chen, Wang: "Bid is not required for Bax translocation during UV-induced apoptosis." in: Cellular signalling, Vol. 19, Issue 12, pp. 2468-78, (2007) (PubMed).

  • 抗原

    BID (BH3 Interacting Domain Death Agonist (BID))

    别名

    BID

    背景

    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.Tissue specificity: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level)

    分子量

    22 kDa

    基因ID

    637

    UniProt

    P55957

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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