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EZH2 抗体 (AA 156-256)

This anti-EZH2 antibody is a 小鼠 单克隆 antibody detecting EZH2 in WB 和 IF. Suitable for 人, 小鼠, 大鼠, 犬 和 小鸡. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN968906
发货至: 中国

Quick Overview for EZH2 抗体 (AA 156-256) (ABIN968906)

抗原

See all EZH2 抗体
EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

适用

  • 122
  • 43
  • 12
  • 9
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬, 小鸡

宿主

  • 91
  • 32
  • 1
小鼠

克隆类型

  • 77
  • 47
单克隆

标记

  • 72
  • 7
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EZH2 antibody is un-conjugated

应用范围

  • 81
  • 40
  • 40
  • 26
  • 25
  • 21
  • 15
  • 13
  • 12
  • 12
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)

克隆位点

11-EZH2
  • 抗原表位

    • 16
    • 15
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-256

    交叉反应

    犬, 大鼠, 小鼠, 小鸡

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Human EZH2 recombinant protein aa. 156-256

    亚型

    IgG1
  • 说明

    Related Products: ABIN968537, ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20°C.
  • Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: "Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 5925-34, (2001) (PubMed).

    van Kemenade, Raaphorst, Blokzijl, Fieret, Hamer, Satijn, Otte, Meijer: "Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma." in: Blood, Vol. 97, Issue 12, pp. 3896-901, (2001) (PubMed).

  • 抗原

    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

    别名

    EZH2

    背景

    The Polycomb group (PcG) of gene products are essential for the maintenance, but not initiation, of the transcriptionally repressed state of development genes. Those genes encode a structurally diverse group of proteins with conserved functions from flies to human cells and from complexes as a result of mutual associations ultimately influencing gene expression. EZH2 is a human homologue of Drosophil's Enhancer of Zeste gene, an important regulator of homeobox gene expression. The expression of EZH2 was seen in follicular T cells and at different stages during T-cell differentiation. Additionally, in lymphocytes, EZH2 interacts with the signal transduction protein Vav and is highly expressed in a variety of tumors such as lymphoma and prostate. The predicted molecular weight for this protein is approximately 85 kDa (SwissProt:Q15910).

    分子量

    91 kDa

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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