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EZH2 抗体

EZH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030808
发货至: 中国
  • 抗原 See all EZH2 抗体
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 106
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    克隆类型
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    多克隆
    标记
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    This EZH2 antibody is un-conjugated
    应用范围
    • 72
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    Expected species reactivity: Primate, Xenopus
    纯化方法
    Antigen affinity
    免疫原
    This EZH2 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human EZH2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product EZH2 Primary Antibody
  • 应用备注
    Titration of the EZH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the EZH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    别名
    EZH2 (EZH2 产品)
    别名
    ENX-1 antibody, ENX1 antibody, EZH1 antibody, EZH2b antibody, KMT6 antibody, KMT6A antibody, WVS antibody, WVS2 antibody, eya2 antibody, im:7149338 antibody, zgc:136376 antibody, zgc:152758 antibody, EZH2 antibody, enx-1 antibody, enx1 antibody, ezh1 antibody, kmt6 antibody, xez antibody, Enx-1 antibody, Enx1h antibody, mKIAA4065 antibody, ezh2 antibody, olezh2 antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog antibody, EZH2 antibody, ezh2 antibody, Ezh2 antibody, ezh2.L antibody, ezh2.S antibody
    背景
    EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2 contains a SET domain, a signature motif for all known histone lysine methyltransferases except the H3-K79 methyltransferase DOT1, and is therefore likely to be the catalytic subunit. Consequently, EZH2 is thought to regulate gene expression by controlling chromatin structure. Several lines of evidence suggested a critical role for the EZH2 protein during normal and perturbed development of the hematopoietic and central nervous systems. The EZH2 protein has been shown to associate with the VAV1 protooncoprotein and with the XNP protein, the product of a gene associated with mental retardation. Additionally, due to mapping of EZH2 to the 7q35-q36 chromosomal region associated with myeloid disorders, this protein is suggested to participate in the genetic events triggering myeloid leukemia.
    UniProt
    Q15910
    途径
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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