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CTBP1 抗体 (AA 345-441)

Name: CTBP1 抗体 (AA 345-441)
SKU: ABIN968722
Availability: OutOfStock

This anti-CTBP1 antibody is a 小鼠单克隆 antibody detecting CTBP1 in WB 和 IF. Suitable for 人, 小鼠, 大鼠, 犬和小鸡. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of CtBP1 on a BC3H1 cell lysate (Mouse brain smooth muscle-like cells, ATCC CRL-1443). (CTBP1 抗体 (AA 345-441))

Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC CCL-2. (CTBP1 抗体 (AA 345-441))

Western Blotting (WB) image for anti-C-terminal Binding Protein 1 (CTBP1) (AA 345-441) antibody (ABIN968722) (CTBP1 抗体 (AA 345-441))

3 images

(4 references)

产品编号 ABIN968722

发货至: 中国

Datasheet as PDF

Quick Overview for CTBP1 抗体 (AA 345-441) (ABIN968722)

抗原

See all CTBP1 抗体

CTBP1 (C-terminal Binding Protein 1 (CTBP1))

适用

人, 小鼠, 大鼠, 犬, 小鸡

宿主

小鼠

克隆类型

单克隆

标记

This CTBP1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

克隆位点

3-CtBP1

Discover our top product CTBP1 Primary Antibody

抗原表位
26

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8

7

3

3

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2

2

2

1

1

1

1

1

1

1

1

1

1

1

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1

1

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1
AA 345-441

交叉反应

人, 大鼠, 小鸡, 犬

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Mouse CtBP1 aa. 345-441

亚型

IgG1
anti-C-terminal Binding Protein 1 (CTBP1) (AA 1-429) antibody
CTBP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2G7 unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (AA 20-250) antibody
CTBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibody
CTBP1 适用: 人, 小鼠, 大鼠, 犬, Pig, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (AA 413-440) antibody
CTBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) antibody
CTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibody
CTBP1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (Internal Region) antibody
CTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (pSer422) antibody
CTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (AA 409-440), (C-Term) antibody
CTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-C-terminal Binding Protein 1 (CTBP1) (pSer422) antibody
CTBP1 适用: 大鼠, 斑马鱼 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Hildebrand, Soriano: "Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development." in: Molecular and cellular biology, Vol. 22, Issue 15, pp. 5296-307, (2002) (PubMed).

Muraoka, Ichikawa, Shi, Okumura, Taira, Higuchi, Hirano, Hibi, Miki: "Kheper, a novel ZFH/deltaEF1 family member, regulates the development of the neuroectoderm of zebrafish (Danio rerio)." in: Developmental biology, Vol. 228, Issue 1, pp. 29-40, (2001) (PubMed).

Furusawa, Moribe, Kondoh, Higashi: "Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8581-90, (2000) (PubMed).

Schaeper, Boyd, Verma, Uhlmann, Subramanian, Chinnadurai: "Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 23, pp. 10467-71, (1995) (PubMed).
抗原

CTBP1 (C-terminal Binding Protein 1 (CTBP1))

别名

CtBP1

背景

Transcriptional repression is critical for genetic regulation of many cellular proteins, and involves either a transcription regulator that has an intrinsic repressor domain, or a transcription regulator that contains a binding site in the regulatory domain where a corepressor can bind. C-terminal binding proteins (CtBP1 and CtBP2) are a class of corepressors that interact with a subset of transcription factors through a PLDLSL sequence motif. CtBP1 and CtBP2 are 80% homologous, and both are expressed at high levels in embryonic tissues. However, CtBP1 is expressed higher in adult tissues, and is more widely expressed in embryonic and adult tissues. Both CtBP1 and CtBP2 bind the deltaEF1 zinc finger-homeodomain transcription factor, and enhance transcriptional repression via interaction with the PLDLSL-sequence in deltaEF1. CtBP1 and CtBP2 bind other zinc finger transcription factors, including Kheper and BKLF. In addition, CtBP2 interacts with other transcription factors, such as hFOG-2, Evi-1, AREB6, and ZEB. Thus, CtBP1 and CtBP2 may be important corepressors for a variety of transcriptional factors. This antibody is routinely tested by western blot analysis.
Synonyms: C-terminal Binding Protein-1

分子量

48 kDa

途径

Retinoic Acid Receptor Signaling Pathway