RAC1 抗体
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北京 101111
Quick Overview for RAC1 抗体 (ABIN968088)
抗原
See all RAC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 小鸡, 犬, 小鼠, 大鼠
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产品特性
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Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Positive Control: Rat Cerebrum -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG2b kappa
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anti-RAC1 (Center) antibody
适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAC1 antibody适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1301CT276-121-104 unconjugated
anti-RAC1 antibody适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1301CT276-121-104 unconjugated
anti-RAC1 (AA 11-185) antibody适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAC1 (pSer71) antibody适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAC1 antibody适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 13C4 unconjugated
anti-RAC1 (AA 101-192) antibody适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAC1 (Ser71) antibody适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAC1 antibodyKD Validated 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB7360 unconjugated
anti-RAC1 (AA 49-78) antibody适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB11123 unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Aqueous buffered solution containing BSA, glycerol.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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- RAC1
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背景
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Rac1 is a member of the expanding family of Ras-related GTPase proteins. These small proteins have the ability to switch between two different conformational states: the active (GTP-bound) and the inactive (GDP-bound). The GTPase activity is increased by specific activator proteins named GAPs. Rac1, contains the consensus sequence Cys-X-X-X-COOH, which localizes it to the plasma membrane. Growth factor stimulation of cells results in a dramatic reorganization of the actin filament network and membrane ruffling, processes for which Rac1 is essential. Constitutive expression of Rac1 leads to cell transformation. This process is mediated by the Rac1-dependent activation of the p65PAK serine/threonine kinase. IQGAP1 has been identified as a GTPase activating protein specific for Rac1.
Testing in native ELISA with recombinant proteins to CDC42 and Rho have shown that the antibody to Rac1 (cat No ABIN968088/1) recognizes CDC42 and Rho. Due to sequence homology among various small GTPase familyl members, potential reactivity could be observed with other family members. -
分子量
- 21 kDa
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途径
- WNT signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
抗原
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