RAC1 抗体
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- 抗原 See all RAC1 抗体
- RAC1
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适用
- 人, 小鼠, 大鼠, 犬, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 小鸡, 犬, 小鼠, 大鼠
- 产品特性
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Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Positive Control: Rat Cerebrum - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 102-Rac1
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product RAC1 Primary Antibody
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anti-RAC1 (Center) antibody
适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAC1 (AA 1-192) antibody适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAC1 antibody适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1301CT276-121-104 unconjugated
anti-RAC1 (AA 11-185) antibody适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAC1 antibody适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1301CT276-121-104 unconjugated
anti-RAC1 (pSer71) antibody适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAC1 (AA 101-192) antibody适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAC1 antibody适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 13C4 unconjugated
anti-RAC1 (AA 100-192) antibody (Biotin)适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-RAC1 (AA 100-192) antibody (PE)适用: 人 WB, IHC 宿主: 兔 Polyclonal PE
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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- 抗原
- RAC1
- Abstract
- RAC1 产品
- 别名
- Rac-1 antibody, TC-25 antibody, p21-Rac1 antibody, AL023026 antibody, D5Ertd559e antibody, RAC2 antibody, CRAC1A antibody, rac1 antibody, wu:fd16e02 antibody, zgc:55823 antibody, zgc:55917 antibody, zgc:86934 antibody, 2248 antibody, CG2248 antibody, D-Rac antibody, D-Rac 1 antibody, D-Rac1 antibody, DRac antibody, DRac1 antibody, DRacA antibody, Dm Rac1 antibody, DmRAC antibody, DmRAC1 antibody, Dmel\CG2248 antibody, Dmrac1 antibody, Drac antibody, Drac1 antibody, Drac1a antibody, DracA antibody, GTPase Rac1 antibody, P40792 antibody, RAC1 antibody, Rac antibody, Rac GTPase antibody, Rac3 antibody, RacA antibody, dRac antibody, dRac1 antibody, drac1 antibody, rac antibody, Xrac antibody, mig5 antibody, p21-rac1 antibody, tc-25 antibody, Rac family small GTPase 1 antibody, RAS-related C3 botulinum substrate 1 antibody, ras-related C3 botulinum toxin substrate 1 antibody, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody, Rac family small GTPase 1a antibody, CG2248 gene product from transcript CG2248-RB antibody, Rac family small GTPase 1 L homeolog antibody, ras homolog family member G antibody, RAC1 antibody, Rac1 antibody, rac1a antibody, rac1.L antibody, RHOG antibody
- 背景
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Rac1 is a member of the expanding family of Ras-related GTPase proteins. These small proteins have the ability to switch between two different conformational states: the active (GTP-bound) and the inactive (GDP-bound). The GTPase activity is increased by specific activator proteins named GAPs. Rac1, contains the consensus sequence Cys-X-X-X-COOH, which localizes it to the plasma membrane. Growth factor stimulation of cells results in a dramatic reorganization of the actin filament network and membrane ruffling, processes for which Rac1 is essential. Constitutive expression of Rac1 leads to cell transformation. This process is mediated by the Rac1-dependent activation of the p65PAK serine/threonine kinase. IQGAP1 has been identified as a GTPase activating protein specific for Rac1.
Testing in native ELISA with recombinant proteins to CDC42 and Rho have shown that the antibody to Rac1 (cat No ABIN968088/1) recognizes CDC42 and Rho. Due to sequence homology among various small GTPase familyl members, potential reactivity could be observed with other family members. - 分子量
- 21 kDa
- 途径
- WNT signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
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