我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

JUP 抗体 (AA 553-738)

Name: JUP 抗体 (AA 553-738)
SKU: ABIN967860
Availability: OutOfStock

This anti-JUP antibody is a 小鼠单克隆 antibody detecting JUP in WB, IF, IHC 和 IP. Suitable for 人, 小鼠, 大鼠, 小鸡和犬. This Primary Antibody has been cited in 6+ publications.

Western blot analysis of gamma-Catenin on a HeLa lysate. (JUP 抗体 (AA 553-738))

Immunofluorescence staining of MCF7 cells. (JUP 抗体 (AA 553-738))

Image no. 3 for anti-Junction Plakoglobin (JUP) (AA 553-738) antibody (ABIN967860) (JUP 抗体 (AA 553-738))

3 images

(6 references)

产品编号 ABIN967860

发货至: 中国

Quick Overview for JUP 抗体 (AA 553-738) (ABIN967860)

抗原

See all JUP 抗体

JUP (Junction Plakoglobin (JUP))

适用

人, 小鼠, 大鼠, 小鸡, 犬

宿主

小鼠

克隆类型

单克隆

标记

This JUP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

15-gamma

Discover our top product JUP Primary Antibody

抗原表位
15

15

11

9

9

6

3

2

2

2

2

1

1

1

1

1

1

1
AA 553-738

交叉反应

小鸡, 犬, 小鼠, 大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human gamma-Catenin aa. 553-738

亚型

IgG2a
anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C12 unconjugated

anti-Junction Plakoglobin (JUP) (AA 1-745) antibody
JUP 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated

anti-Junction Plakoglobin (JUP) (C-Term) antibody
JUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated

anti-Junction Plakoglobin (JUP) (C-Term) antibody
Verified JUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Junction Plakoglobin (JUP) (AA 556-745) antibody
JUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal CTNG-1664 unconjugated

anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat WB, IF, FACS 宿主: 小鼠 Monoclonal 15F11 unconjugated

anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1-10E05 unconjugated

anti-Junction Plakoglobin (JUP) (AA 1-300) antibody
JUP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968535, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Akins, Greer: "Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion." in: The Journal of comparative neurology, Vol. 499, Issue 6, pp. 979-89, (2007) (PubMed).

Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).

Merritt, Berika, Zhai, Kirk, Ji, Hardman, Garrod: "Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5846-58, (2002) (PubMed).

Peng, Mandai, Nakanishi, Ikeda, Asada, Momose, Shibamoto, Yanagihara, Shiozaki, Monden, Takeichi, Takai: "Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line." in: Oncogene, Vol. 21, Issue 26, pp. 4108-19, (2002) (PubMed).

Müller, Choidas, Reichmann, Ullrich: "Phosphorylation and free pool of beta-catenin are regulated by tyrosine kinases and tyrosine phosphatases during epithelial cell migration." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10173-83, (1999) (PubMed).

McCrea, Turck, Gumbiner: "A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin." in: Science (New York, N.Y.), Vol. 254, Issue 5036, pp. 1359-61, (1992) (PubMed).
抗原

JUP (Junction Plakoglobin (JUP))

别名

gamma-Catenin

背景

Gamma-Catenin (plakoglobin) was identified as a compenent of desmosomes where it associates with desmoglein. gamma-Catenin and beta-Catenin are closely related proteins that have significant homology with the Drosophila armadillo protein. In addition to complexing with E-Cadherin, gamma-Catenin and beta-Catenin have been observed in association with the intracellular domain of N-Cadherin. It has been proposed that one molecule of alpha-Catenin and at least one molecule of beta-Catenin and gamma-Catenin simultaneously bind to a single cadherin molecule. A 19 amino acid sequence of desmoglein (Dsg1) was found to be critical for binding of gamma-Catenin. This region has significant homology to the catenin-binding domain of classical cadherins, thus suggesting a common mechanism for gamma-Catenin localization at both adherens junctions and desmosomes.
This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

分子量

82 kDa

途径

Cell-Cell Junction Organization, Maintenance of Protein Location